| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DNMT1 | DNMT3B | ENSAPLP00000002034 | ENSAPLP00000018469 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA methyltransferase 3 beta. | 0.998 |
| DNMT1 | TRDMT1 | ENSAPLP00000002034 | ENSAPLP00000004207 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.692 |
| DNMT3B | DNMT1 | ENSAPLP00000018469 | ENSAPLP00000002034 | DNA methyltransferase 3 beta. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.998 |
| DNMT3B | TRDMT1 | ENSAPLP00000018469 | ENSAPLP00000004207 | DNA methyltransferase 3 beta. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.719 |
| NSUN2 | NSUN6 | ENSAPLP00000011355 | ENSAPLP00000013296 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.836 |
| NSUN2 | NSUN7 | ENSAPLP00000011355 | ENSAPLP00000028797 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.809 |
| NSUN2 | TRDMT1 | ENSAPLP00000011355 | ENSAPLP00000004207 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.908 |
| NSUN2 | TRMT10A | ENSAPLP00000011355 | ENSAPLP00000002223 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA methyltransferase 10A. | 0.509 |
| NSUN2 | TRMT10C | ENSAPLP00000011355 | ENSAPLP00000011302 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA methyltransferase 10C, mitochondrial RNase P subunit. | 0.640 |
| NSUN2 | TRMT11 | ENSAPLP00000011355 | ENSAPLP00000001821 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA methyltransferase 11 homolog. | 0.632 |
| NSUN2 | WDR4 | ENSAPLP00000011355 | ENSAPLP00000006821 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.798 |
| NSUN6 | NSUN2 | ENSAPLP00000013296 | ENSAPLP00000011355 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.836 |
| NSUN6 | NSUN7 | ENSAPLP00000013296 | ENSAPLP00000028797 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.835 |
| NSUN6 | TRDMT1 | ENSAPLP00000013296 | ENSAPLP00000004207 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.852 |
| NSUN6 | TRMT10A | ENSAPLP00000013296 | ENSAPLP00000002223 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA methyltransferase 10A. | 0.506 |
| NSUN6 | TRMT10C | ENSAPLP00000013296 | ENSAPLP00000011302 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA methyltransferase 10C, mitochondrial RNase P subunit. | 0.609 |
| NSUN6 | TRMT11 | ENSAPLP00000013296 | ENSAPLP00000001821 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA methyltransferase 11 homolog. | 0.509 |
| NSUN6 | WDR4 | ENSAPLP00000013296 | ENSAPLP00000006821 | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.654 |
| NSUN7 | NSUN2 | ENSAPLP00000028797 | ENSAPLP00000011355 | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.809 |
| NSUN7 | NSUN6 | ENSAPLP00000028797 | ENSAPLP00000013296 | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.835 |