Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ESM1Endothelial cell specific molecule 1. (206 aa)    
Predicted Functional Partners:
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.715
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
      
 0.661
CHRNA9
Cholinergic receptor nicotinic alpha 9 subunit.
      
 0.605
EMCN
Endomucin.
   
  
 0.591
APLN
Apelin.
      
 0.545
TSPAN12
Tetraspanin.
     
 0.523
RALB
RAS like proto-oncogene B.
     
 0.516
PLCE1
Phosphoinositide phospholipase C.
     
 0.509
ADRA2C
Adrenoceptor alpha 2C.
     
 0.507
GRK5
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    
 
 0.506
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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