STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESM1Endothelial cell specific molecule 1. (206 aa)    
Predicted Functional Partners:
CHRNA9
Cholinergic receptor nicotinic alpha 9 subunit.
      
 0.716
SHANK2
SH3 and multiple ankyrin repeat domains 2.
    
 
 0.632
GLI2
Uncharacterized protein.
     
 0.559
HSD17B12
Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.541
ID3
Inhibitor of DNA binding 3, HLH protein.
      
 0.497
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
     
 0.490
MC1R
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
     
 0.458
CNTN1
Contactin 1.
      
 0.456
MITF
Melanocyte inducing transcription factor.
      
 0.452
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.452
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.