Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KSR2Kinase suppressor of ras 2. (557 aa)    
Predicted Functional Partners:
BRAP
BRCA1 associated protein.
    
  0.822
U3IU71_ANAPP
Protein kinase domain-containing protein.
   
 0.791
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.791
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
 0.789
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.785
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.785
U3IK86_ANAPP
PH domain-containing protein.
    
 0.760
U3IIV7_ANAPP
Uncharacterized protein.
    
 0.700
CNKSR2
Connector enhancer of kinase suppressor of Ras 2.
    
 0.700
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
    
 0.671
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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