STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KSR2Kinase suppressor of ras 2. (557 aa)    
Predicted Functional Partners:
U3IU71_ANAPP
Protein kinase domain-containing protein.
   
 0.778
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.778
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
0.778
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.708
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
0.705
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
   
 0.700
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.647
METTL6
Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family.
    
 
 0.638
U3IK86_ANAPP
PH domain-containing protein.
    
 0.623
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
   
 0.611
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.