Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SKA1Uncharacterized protein. (104 aa)    
Predicted Functional Partners:
SKA2
Spindle and kinetochore associated complex subunit 2.
    
 0.996
ENSAPLP00000025418
Uncharacterized protein.
   
 0.991
NDC80
NDC80 kinetochore complex component.
   
 0.940
NUDC
Nuclear distribution C, dynein complex regulator.
     
  0.936
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.912
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.907
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.895
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.894
SGO1
Shugoshin 1.
   
 
 0.883
ZW10
Zw10 kinetochore protein.
      
 0.846
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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