STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (651 aa)    
Predicted Functional Partners:
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.974
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
0.942
CYP39A1
Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
0.941
DHCR7
7-dehydrocholesterol reductase.
   
 0.930
POR
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
 
  
 
 0.926
CYP27A1
Cytochrome P450 family 27 subfamily A member 1.
    
 0.909
SOAT1
O-acyltransferase.
    
 0.846
DHCR24
24-dehydrocholesterol reductase.
   
 0.844
LIPA
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
  
 0.809
ENSAPLP00000017946
AB hydrolase-1 domain-containing protein.
  
 0.809
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.