Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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USP16Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (819 aa)    
Predicted Functional Partners:
USP45
Ubiquitin carboxyl-terminal hydrolase.
  
  
 
0.904
ENSAPLP00000023897
Uncharacterized protein.
    
  0.885
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.798
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1.
    
 
 0.660
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
    
 
 0.660
ZRANB1
Zinc finger RANBP2-type containing 1.
    
 
 0.654
U3IYM6_ANAPP
Uncharacterized protein.
      
 0.605
GTF2A1L
General transcription factor IIA subunit 1 like.
   
  
 0.600
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.582
UBE2J2
Ubiquitin conjugating enzyme E2 J2.
      
 0.549
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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