STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC4SHC adaptor protein 4. (631 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.971
EGFR
Receptor protein-tyrosine kinase.
    
 0.966
ERBB4
Receptor protein-tyrosine kinase.
    
 0.966
INSR
Tyrosine-protein kinase receptor.
    
 0.951
SHC3
SHC adaptor protein 3.
  
 
 
0.924
SHC1
SHC adaptor protein 1.
    
 
0.923
FYN
Tyrosine-protein kinase.
    
 0.919
PTK2
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.911
IGF1R
Tyrosine-protein kinase receptor.
    
 0.829
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.815
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.