STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC4SHC adaptor protein 4. (631 aa)    
Predicted Functional Partners:
EGFR
Receptor protein-tyrosine kinase.
    
 0.964
ERBB4
Receptor protein-tyrosine kinase.
    
 0.964
GRB2
Growth factor receptor bound protein 2.
   
 0.960
INSR
Tyrosine-protein kinase receptor.
    
 0.953
SHC1
SHC adaptor protein 1.
    
 
0.910
PTK2
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.910
SHC2
Uncharacterized protein.
     
 
0.902
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.879
IGF1R
Tyrosine-protein kinase receptor.
    
 0.837
INPPL1
Inositol polyphosphate phosphatase like 1.
    
 0.787
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.