STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)    
Predicted Functional Partners:
CTNND1
Uncharacterized protein.
   
 0.903
GRB2
Growth factor receptor bound protein 2.
   
0.880
GAB1
GRB2 associated binding protein 1.
    
 0.866
SYK
Spleen associated tyrosine kinase.
   
0.857
JAK1
Tyrosine-protein kinase.
   
 0.793
CD247
CD247 molecule.
   
 0.752
LYN
Tyrosine-protein kinase.
   
 0.750
INPP5D
SH2 domain-containing protein.
   
 0.749
CD3E
CD3e molecule.
   
 0.716
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.713
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.