PAX6 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PAX6

Paired box 6. (429 aa)

Predicted Functional Partners:

SIX3

0.830

NKX2-2

0.816

SHH

0.803

NEUROD1

0.791

TIMM22

0.782

FOXG1

0.761

TBR1

0.755

ENSAPLP00000018750

0.755

INS

0.735

OLIG2

0.727

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000018750	FOXG1	ENSAPLP00000018750	ENSAPLP00000032910	Uncharacterized protein.	Forkhead box G1.	0.637
ENSAPLP00000018750	NEUROD1	ENSAPLP00000018750	ENSAPLP00000027375	Uncharacterized protein.	Neurogenic differentiation factor.	0.478
ENSAPLP00000018750	OLIG2	ENSAPLP00000018750	ENSAPLP00000021362	Uncharacterized protein.	Oligodendrocyte transcription factor 2.	0.479
ENSAPLP00000018750	PAX6	ENSAPLP00000018750	ENSAPLP00000004507	Uncharacterized protein.	Paired box 6.	0.755
ENSAPLP00000018750	TBR1	ENSAPLP00000018750	ENSAPLP00000007952	Uncharacterized protein.	Uncharacterized protein.	0.918
FOXG1	ENSAPLP00000018750	ENSAPLP00000032910	ENSAPLP00000018750	Forkhead box G1.	Uncharacterized protein.	0.637
FOXG1	NEUROD1	ENSAPLP00000032910	ENSAPLP00000027375	Forkhead box G1.	Neurogenic differentiation factor.	0.583
FOXG1	PAX6	ENSAPLP00000032910	ENSAPLP00000004507	Forkhead box G1.	Paired box 6.	0.761
FOXG1	SHH	ENSAPLP00000032910	ENSAPLP00000006846	Forkhead box G1.	Sonic hedgehog signaling molecule.	0.624
FOXG1	SIX3	ENSAPLP00000032910	ENSAPLP00000020924	Forkhead box G1.	SIX homeobox 3.	0.617
FOXG1	TBR1	ENSAPLP00000032910	ENSAPLP00000007952	Forkhead box G1.	Uncharacterized protein.	0.637
INS	NEUROD1	ENSAPLP00000012854	ENSAPLP00000027375	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenic differentiation factor.	0.603
INS	NKX2-2	ENSAPLP00000012854	ENSAPLP00000026489	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Homeobox domain-containing protein.	0.694
INS	PAX6	ENSAPLP00000012854	ENSAPLP00000004507	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 6.	0.735
INS	SHH	ENSAPLP00000012854	ENSAPLP00000006846	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Sonic hedgehog signaling molecule.	0.621
NEUROD1	ENSAPLP00000018750	ENSAPLP00000027375	ENSAPLP00000018750	Neurogenic differentiation factor.	Uncharacterized protein.	0.478
NEUROD1	FOXG1	ENSAPLP00000027375	ENSAPLP00000032910	Neurogenic differentiation factor.	Forkhead box G1.	0.583
NEUROD1	INS	ENSAPLP00000027375	ENSAPLP00000012854	Neurogenic differentiation factor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.603
NEUROD1	NKX2-2	ENSAPLP00000027375	ENSAPLP00000026489	Neurogenic differentiation factor.	Homeobox domain-containing protein.	0.677
NEUROD1	PAX6	ENSAPLP00000027375	ENSAPLP00000004507	Neurogenic differentiation factor.	Paired box 6.	0.791