Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
U3IB98_ANAPPDHR-1 domain-containing protein; Belongs to the DOCK family. (692 aa)    
Predicted Functional Partners:
ENSAPLP00000029548
DHR-2 domain-containing protein; Belongs to the DOCK family.
 
     0.896
CRK
CRK proto-oncogene, adaptor protein.
    
 0.815
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.720
ELMO3
Engulfment and cell motility 3.
  
 0.697
ELMO2
Engulfment and cell motility 2.
  
 0.684
RHOG-2
Uncharacterized protein.
   
 0.592
RHOG
Ras homolog family member G.
   
 0.592
ELMO1-2
Engulfment and cell motility 1.
   
 0.583
ELMO1
PH domain-containing protein.
   
 0.583
ENSAPLP00000021914
Uncharacterized protein.
   
 0.583
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (12%) [HD]