STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPLPeriplakin. (1531 aa)    
Predicted Functional Partners:
EVPL
SH3_10 domain-containing protein.
  
  
0.934
EZR
Ezrin.
   
 
 0.842
U3IDY1_ANAPP
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.652
KAZN
Kazrin, periplakin interacting protein.
    
 0.651
JUP
Junction plakoglobin.
   
 0.628
TGM6
Transglutaminase 6.
   
 
 0.592
PKP1
Plakophilin 1.
    
 0.544
A2ML1
Alpha-2-macroglobulin like 1.
      
 0.544
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
      
 0.524
ZNF592
Zinc finger protein 592.
    
 0.487
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.