Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAPK6Mitogen-activated protein kinase 6. (721 aa)    
Predicted Functional Partners:
U3ILW2_ANAPP
Protein kinase domain-containing protein.
    
 0.996
MAPK4
Mitogen-activated protein kinase 4; Belongs to the protein kinase superfamily.
   
 
  0.993
PAK2
CRIB domain-containing protein.
   
 0.947
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.805
CDC14A
Cell division cycle 14A.
    
 0.753
CDC14B
Uncharacterized protein.
    
 0.731
CDC42
Cell division cycle 42.
   
 0.716
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1.
    
 0.714
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
    
 0.714
XPO1
CRM1_C domain-containing protein.
    
 0.700
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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