Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CGRRF1Cell growth regulator with ring finger domain 1. (282 aa)    
Predicted Functional Partners:
RNF185
Ring finger protein 185.
      
 0.664
ANKLE2
Ankyrin repeat and LEM domain containing 2.
    
 
 0.653
RNF130
Ring finger protein 130.
     
 0.646
FAM8A1
Family with sequence similarity 8 member A1.
      
 0.636
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
      
 0.595
RNF170
Ring finger protein 170.
      
 0.595
RNF19B
Ring finger protein 19B.
    
 0.573
CNIH1
Cornichon family AMPA receptor auxiliary protein 1.
      
 0.548
LSG1
CP-type G domain-containing protein.
      
 0.545
RNF145
Ring finger protein 145.
    
 
 0.524
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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