STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (106 aa)    
Predicted Functional Partners:
PTH1R
Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family.
   
 0.992
U3IRJ0_ANAPP
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
   
 0.914
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
      
 0.906
PTHLH
Parathyroid hormone like hormone.
     
 0.888
CASR
Calcium sensing receptor.
      
 0.854
SOST
Sclerostin.
      
 0.783
PNMT
Phenylethanolamine N-methyltransferase.
      
 0.769
ENSAPLP00000027063
Osteocalcin; Binds strongly to apatite and calcium.
      
 0.752
VDR
Vitamin D receptor.
      
 0.751
GC
GC vitamin D binding protein.
      
 0.711
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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