PPM1A protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PPM1A

Protein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)

Predicted Functional Partners:

MAP2K4

0.928

PPM1B

0.927

MAP2K3

0.920

MAP2K6

0.920

SMAD2

0.719

SMAD3

0.719

SMAD4

0.636

SLC3A1

0.627

EXOC5

0.606

ZDHHC1

0.573

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EXOC5	PPM1A	ENSAPLP00000030107	ENSAPLP00000004676	Exocyst complex component 5.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.606
EXOC5	PPM1B	ENSAPLP00000030107	ENSAPLP00000022490	Exocyst complex component 5.	PPM-type phosphatase domain-containing protein.	0.484
MAP2K3	MAP2K6	ENSAPLP00000017618	ENSAPLP00000028680	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	0.902
MAP2K3	PPM1A	ENSAPLP00000017618	ENSAPLP00000004676	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.920
MAP2K4	PPM1A	ENSAPLP00000012899	ENSAPLP00000004676	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.928
MAP2K6	MAP2K3	ENSAPLP00000028680	ENSAPLP00000017618	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.902
MAP2K6	PPM1A	ENSAPLP00000028680	ENSAPLP00000004676	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.920
PPM1A	EXOC5	ENSAPLP00000004676	ENSAPLP00000030107	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Exocyst complex component 5.	0.606
PPM1A	MAP2K3	ENSAPLP00000004676	ENSAPLP00000017618	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.920
PPM1A	MAP2K4	ENSAPLP00000004676	ENSAPLP00000012899	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.928
PPM1A	MAP2K6	ENSAPLP00000004676	ENSAPLP00000028680	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	0.920
PPM1A	PPM1B	ENSAPLP00000004676	ENSAPLP00000022490	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	PPM-type phosphatase domain-containing protein.	0.927
PPM1A	SLC3A1	ENSAPLP00000004676	ENSAPLP00000008251	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Solute carrier family 3 member 1.	0.627
PPM1A	SMAD2	ENSAPLP00000004676	ENSAPLP00000004542	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Mothers against decapentaplegic homolog.	0.719
PPM1A	SMAD3	ENSAPLP00000004676	ENSAPLP00000006649	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Mothers against decapentaplegic homolog.	0.719
PPM1A	SMAD4	ENSAPLP00000004676	ENSAPLP00000003446	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Mothers against decapentaplegic homolog.	0.636
PPM1A	ZDHHC1	ENSAPLP00000004676	ENSAPLP00000009160	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.573
PPM1B	EXOC5	ENSAPLP00000022490	ENSAPLP00000030107	PPM-type phosphatase domain-containing protein.	Exocyst complex component 5.	0.484
PPM1B	PPM1A	ENSAPLP00000022490	ENSAPLP00000004676	PPM-type phosphatase domain-containing protein.	Protein phosphatase, Mg2+/Mn2+ dependent 1A.	0.927
PPM1B	SLC3A1	ENSAPLP00000022490	ENSAPLP00000008251	PPM-type phosphatase domain-containing protein.	Solute carrier family 3 member 1.	0.669