Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)    
Predicted Functional Partners:
AIFM1
Apoptosis inducing factor mitochondria associated 1.
  
 0.908
ENSAPLP00000028245
Uncharacterized protein.
   
 0.898
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.895
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 
 0.883
ENSAPLP00000031478
PARP-type domain-containing protein.
   
 
 0.883
APLF
Aprataxin and PNKP like factor.
    
 
 0.863
MACROH2A2
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
   
  0.847
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
   0.798
XRCC6
X-ray repair cross complementing 6.
    
 0.795
ATRX
ATRX chromatin remodeler.
    
 0.787
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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