Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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co-expression
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[Homology]
Score
HPS5Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (968 aa)    
Predicted Functional Partners:
ENSAPLP00000023398
Uncharacterized protein.
 
     0.949
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.
    
 0.925
HPS3
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.
   
 0.889
BLOC1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
     
 0.696
ENSAPLP00000026067
Uncharacterized protein.
     
 0.594
BLOC1S5
Uncharacterized protein.
     
 0.571
GGCX
Gamma-glutamyl carboxylase.
      
 0.562
BLOC1S2
Biogenesis of lysosomal organelles complex 1 subunit 2.
    
 0.556
FRMD7
FERM domain containing 7.
      
 0.517
VPS41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
 
 0.506
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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