Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FASLGFas ligand; Belongs to the tumor necrosis factor family. (237 aa)    
Predicted Functional Partners:
FAS
Uncharacterized protein.
    
 0.999
FADD
Uncharacterized protein.
    
 0.992
CASP8
Caspase 8; Belongs to the peptidase C14A family.
    
 0.918
U3J6D9_ANAPP
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.918
CASP10
Caspase 10; Belongs to the peptidase C14A family.
    
 0.918
U3J6Z6_ANAPP
Uncharacterized protein.
    
 
 0.888
CFLAR
CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.
    
 0.885
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
    
 
 0.866
BCL2
BCL2 apoptosis regulator.
      
 0.848
U3IDI2_ANAPP
Uncharacterized protein.
    
 0.814
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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