DSTYK protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DSTYK

Dual serine/threonine and tyrosine protein kinase. (857 aa)

Predicted Functional Partners:

NKTR

0.735

BYSL

0.728

SCAMP3

0.719

ATOH8

0.719

RBBP5

0.677

FAXC

0.668

MED20

0.655

ENSAPLP00000029952

0.610

FBXW11

0.606

TMTC2

0.580

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOH8	DSTYK	ENSAPLP00000030333	ENSAPLP00000004905	Atonal bHLH transcription factor 8.	Dual serine/threonine and tyrosine protein kinase.	0.719
ATOH8	FBXW11	ENSAPLP00000030333	ENSAPLP00000009703	Atonal bHLH transcription factor 8.	F-box and WD repeat domain containing 11.	0.560
ATOH8	NKTR	ENSAPLP00000030333	ENSAPLP00000028754	Atonal bHLH transcription factor 8.	Natural killer cell triggering receptor.	0.719
ATOH8	SCAMP3	ENSAPLP00000030333	ENSAPLP00000022787	Atonal bHLH transcription factor 8.	Secretory carrier-associated membrane protein.	0.719
BYSL	DSTYK	ENSAPLP00000008423	ENSAPLP00000004905	Bystin like.	Dual serine/threonine and tyrosine protein kinase.	0.728
BYSL	MED20	ENSAPLP00000008423	ENSAPLP00000020482	Bystin like.	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.682
DSTYK	ATOH8	ENSAPLP00000004905	ENSAPLP00000030333	Dual serine/threonine and tyrosine protein kinase.	Atonal bHLH transcription factor 8.	0.719
DSTYK	BYSL	ENSAPLP00000004905	ENSAPLP00000008423	Dual serine/threonine and tyrosine protein kinase.	Bystin like.	0.728
DSTYK	ENSAPLP00000029952	ENSAPLP00000004905	ENSAPLP00000029952	Dual serine/threonine and tyrosine protein kinase.	Kazal-like domain-containing protein.	0.610
DSTYK	FAXC	ENSAPLP00000004905	ENSAPLP00000006047	Dual serine/threonine and tyrosine protein kinase.	Failed axon connections homolog, metaxin like GST domain containing.	0.668
DSTYK	FBXW11	ENSAPLP00000004905	ENSAPLP00000009703	Dual serine/threonine and tyrosine protein kinase.	F-box and WD repeat domain containing 11.	0.606
DSTYK	MED20	ENSAPLP00000004905	ENSAPLP00000020482	Dual serine/threonine and tyrosine protein kinase.	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.655
DSTYK	NKTR	ENSAPLP00000004905	ENSAPLP00000028754	Dual serine/threonine and tyrosine protein kinase.	Natural killer cell triggering receptor.	0.735
DSTYK	RBBP5	ENSAPLP00000004905	ENSAPLP00000005182	Dual serine/threonine and tyrosine protein kinase.	RB binding protein 5, histone lysine methyltransferase complex subunit.	0.677
DSTYK	SCAMP3	ENSAPLP00000004905	ENSAPLP00000022787	Dual serine/threonine and tyrosine protein kinase.	Secretory carrier-associated membrane protein.	0.719
DSTYK	TMTC2	ENSAPLP00000004905	ENSAPLP00000017728	Dual serine/threonine and tyrosine protein kinase.	Transmembrane O-mannosyltransferase targeting cadherins 2.	0.580
ENSAPLP00000029952	DSTYK	ENSAPLP00000029952	ENSAPLP00000004905	Kazal-like domain-containing protein.	Dual serine/threonine and tyrosine protein kinase.	0.610
FAXC	DSTYK	ENSAPLP00000006047	ENSAPLP00000004905	Failed axon connections homolog, metaxin like GST domain containing.	Dual serine/threonine and tyrosine protein kinase.	0.668
FAXC	TMTC2	ENSAPLP00000006047	ENSAPLP00000017728	Failed axon connections homolog, metaxin like GST domain containing.	Transmembrane O-mannosyltransferase targeting cadherins 2.	0.651
FBXW11	ATOH8	ENSAPLP00000009703	ENSAPLP00000030333	F-box and WD repeat domain containing 11.	Atonal bHLH transcription factor 8.	0.560