Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
UFL1UFM1 specific ligase 1. (789 aa)    
Predicted Functional Partners:
CDK5RAP3
CDK5 regulatory subunit associated protein 3.
   
 
 0.993
ENSAPLP00000016691
Uncharacterized protein.
    
 
 0.979
UFM1
Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.
   
 
 0.930
UBA5
Ubiquitin like modifier activating enzyme 5.
   
 
 0.838
ENSAPLP00000025536
Ubiquitin-like domain-containing protein.
    
 0.785
RPL26
Ribosomal protein L26.
    
 
 0.744
SRPRB
Uncharacterized protein.
      
 0.743
UFSP2
UFM1 specific peptidase 2.
   
  
 0.707
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
    
 
 0.685
RPL12
Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family.
    
 
 0.651
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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