Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (962 aa)    
Predicted Functional Partners:
WDR61
WD repeat domain 61.
    
 0.999
CDC73
Cell division cycle 73.
   
 0.999
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.999
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.998
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.964
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.954
SUPT16H-2
Uncharacterized protein.
   
 0.938
SUPT6H
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
   
 0.932
IWS1
TFIIS N-terminal domain-containing protein.
   
 0.922
SUPT5H
SPT5 homolog, DSIF elongation factor subunit.
   
 0.917
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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