Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
U3ICJ6_ANAPPUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)    
Predicted Functional Partners:
OXCT1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
     
 0.963
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.
     
 0.945
AACS
Uncharacterized protein.
     
 0.912
ENSAPLP00000026737
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.902
PRPSAP2
Pribosyltran_N domain-containing protein.
     
 0.569
ACAT1
Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.494
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
      
 0.482
U3I6B7_ANAPP
CTP_transf_like domain-containing protein.
    
 
 0.481
BDH2
3-hydroxybutyrate dehydrogenase 2.
   
 
 0.455
ACADM
Acyl-CoA dehydrogenase medium chain.
   
 
 0.447
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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