Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
PSAT1Phosphoserine aminotransferase. (340 aa)    
Predicted Functional Partners:
PHGDH
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.999
PSPH
Phosphoserine phosphatase.
  
 
 0.998
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.886
U3IZ19_ANAPP
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.790
CTBP2
C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.790
CTBP1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.790
SHMT1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.775
CEP78
Centrosomal protein 78.
 
    
 0.768
ENSAPLP00000022879
Alkaline phosphatase.
     
 0.759
ASNS
Asparagine synthetase [glutamine-hydrolyzing].
   
  
 0.722
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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