Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AP3S2Adaptor related protein complex 3 subunit sigma 2. (193 aa)    
Predicted Functional Partners:
AP3D1
Adaptor related protein complex 3 subunit delta 1.
    
 0.983
AP3B1
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.978
AP3B2
Adaptor related protein complex 3 subunit beta 2.
    
 0.978
AP3M1
AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.
   
 0.971
AP3M2
AP-3 complex subunit mu-2.
   
 0.971
RPL7A
Ribosomal_L7Ae domain-containing protein.
 
    
 0.906
AP3S1
Adaptor related protein complex 3 subunit sigma 1.
  
  
 
0.901
AP1M1
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
     
 0.881
AP1G1
AP-1 complex subunit gamma.
    
 0.851
GAK
Cyclin G associated kinase.
    
 0.844
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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