| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACLY | CS | ENSAPLP00000016003 | ENSAPLP00000032070 | Ligase_CoA domain-containing protein. | Citrate synthase; Belongs to the citrate synthase family. | 0.990 |
| ACLY | DLAT | ENSAPLP00000016003 | ENSAPLP00000005029 | Ligase_CoA domain-containing protein. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.978 |
| ACLY | DLD | ENSAPLP00000016003 | ENSAPLP00000009721 | Ligase_CoA domain-containing protein. | Dihydrolipoyl dehydrogenase. | 0.607 |
| ACLY | ENSAPLP00000024157 | ENSAPLP00000016003 | ENSAPLP00000024157 | Ligase_CoA domain-containing protein. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.481 |
| ACLY | PDHA1 | ENSAPLP00000016003 | ENSAPLP00000016862 | Ligase_CoA domain-containing protein. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.419 |
| ACLY | PDHX | ENSAPLP00000016003 | ENSAPLP00000011507 | Ligase_CoA domain-containing protein. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.726 |
| ACLY | SUCLG1 | ENSAPLP00000016003 | ENSAPLP00000022533 | Ligase_CoA domain-containing protein. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.870 |
| CS | ACLY | ENSAPLP00000032070 | ENSAPLP00000016003 | Citrate synthase; Belongs to the citrate synthase family. | Ligase_CoA domain-containing protein. | 0.990 |
| CS | DLAT | ENSAPLP00000032070 | ENSAPLP00000005029 | Citrate synthase; Belongs to the citrate synthase family. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.995 |
| CS | DLD | ENSAPLP00000032070 | ENSAPLP00000009721 | Citrate synthase; Belongs to the citrate synthase family. | Dihydrolipoyl dehydrogenase. | 0.900 |
| CS | ENSAPLP00000024157 | ENSAPLP00000032070 | ENSAPLP00000024157 | Citrate synthase; Belongs to the citrate synthase family. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.878 |
| CS | GCSH | ENSAPLP00000032070 | ENSAPLP00000029441 | Citrate synthase; Belongs to the citrate synthase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.413 |
| CS | PDHA1 | ENSAPLP00000032070 | ENSAPLP00000016862 | Citrate synthase; Belongs to the citrate synthase family. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.881 |
| CS | PDHX | ENSAPLP00000032070 | ENSAPLP00000011507 | Citrate synthase; Belongs to the citrate synthase family. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.902 |
| CS | PDK3 | ENSAPLP00000032070 | ENSAPLP00000010270 | Citrate synthase; Belongs to the citrate synthase family. | Protein-serine/threonine kinase. | 0.621 |
| CS | SUCLG1 | ENSAPLP00000032070 | ENSAPLP00000022533 | Citrate synthase; Belongs to the citrate synthase family. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.934 |
| DLAT | ACLY | ENSAPLP00000005029 | ENSAPLP00000016003 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Ligase_CoA domain-containing protein. | 0.978 |
| DLAT | CS | ENSAPLP00000005029 | ENSAPLP00000032070 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Citrate synthase; Belongs to the citrate synthase family. | 0.995 |
| DLAT | DLD | ENSAPLP00000005029 | ENSAPLP00000009721 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyl dehydrogenase. | 0.999 |
| DLAT | ENSAPLP00000024157 | ENSAPLP00000005029 | ENSAPLP00000024157 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |