Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MTBPMDM2 binding protein. (879 aa)    
Predicted Functional Partners:
MDM2
Uncharacterized protein.
    
 0.935
ENSAPLP00000026542
SWIB domain-containing protein.
    
 0.878
ENSAPLP00000031075
VWFA domain-containing protein.
    
 
 0.854
TICRR
TOPBP1 interacting checkpoint and replication regulator.
   
 0.816
TOPBP1
DNA topoisomerase II binding protein 1.
   
 
 0.784
RECQL4
RecQ like helicase 4.
   
 
 0.701
CILP2
Cartilage intermediate layer protein 2.
      
 0.667
TBPL2
TATA-box binding protein like 2.
    
 0.659
TBP
TATA-box binding protein.
    
 0.659
MDM4
Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.
    
 0.656
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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