TXNIP protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TXNIP

Thioredoxin interacting protein. (390 aa)

Predicted Functional Partners:

TXN

0.999

TXN2

0.982

U3IRD8_ANAPP

0.947

ITCH

0.945

WWP1

0.904

PTPN11

0.764

U3J954_ANAPP

0.764

SLC2A1

0.761

ENSAPLP00000020265

0.697

U3J1K3_ANAPP

0.686

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000020265	TXN	ENSAPLP00000020265	ENSAPLP00000008437	Uncharacterized protein.	Thioredoxin; Belongs to the thioredoxin family.	0.651
ENSAPLP00000020265	TXNIP	ENSAPLP00000020265	ENSAPLP00000005052	Uncharacterized protein.	Thioredoxin interacting protein.	0.697
ENSAPLP00000020265	U3IRD8_ANAPP	ENSAPLP00000020265	ENSAPLP00000009811	Uncharacterized protein.	Uncharacterized protein.	0.657
ENSAPLP00000020265	U3J1K3_ANAPP	ENSAPLP00000020265	ENSAPLP00000013380	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.998
ITCH	TXNIP	ENSAPLP00000013204	ENSAPLP00000005052	E3 ubiquitin-protein ligase.	Thioredoxin interacting protein.	0.945
ITCH	WWP1	ENSAPLP00000013204	ENSAPLP00000001881	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.970
PTPN11	TXNIP	ENSAPLP00000015227	ENSAPLP00000005052	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Thioredoxin interacting protein.	0.764
PTPN11	U3J954_ANAPP	ENSAPLP00000015227	ENSAPLP00000016032	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.901
SLC2A1	TXNIP	ENSAPLP00000030274	ENSAPLP00000005052	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	Thioredoxin interacting protein.	0.761
TXN	ENSAPLP00000020265	ENSAPLP00000008437	ENSAPLP00000020265	Thioredoxin; Belongs to the thioredoxin family.	Uncharacterized protein.	0.651
TXN	TXN2	ENSAPLP00000008437	ENSAPLP00000031997	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin 2.	0.971
TXN	TXNIP	ENSAPLP00000008437	ENSAPLP00000005052	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin interacting protein.	0.999
TXN	U3J1K3_ANAPP	ENSAPLP00000008437	ENSAPLP00000013380	Thioredoxin; Belongs to the thioredoxin family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.559
TXN2	TXN	ENSAPLP00000031997	ENSAPLP00000008437	Thioredoxin 2.	Thioredoxin; Belongs to the thioredoxin family.	0.971
TXN2	TXNIP	ENSAPLP00000031997	ENSAPLP00000005052	Thioredoxin 2.	Thioredoxin interacting protein.	0.982
TXN2	U3J1K3_ANAPP	ENSAPLP00000031997	ENSAPLP00000013380	Thioredoxin 2.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.457
TXNIP	ENSAPLP00000020265	ENSAPLP00000005052	ENSAPLP00000020265	Thioredoxin interacting protein.	Uncharacterized protein.	0.697
TXNIP	ITCH	ENSAPLP00000005052	ENSAPLP00000013204	Thioredoxin interacting protein.	E3 ubiquitin-protein ligase.	0.945
TXNIP	PTPN11	ENSAPLP00000005052	ENSAPLP00000015227	Thioredoxin interacting protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.764
TXNIP	SLC2A1	ENSAPLP00000005052	ENSAPLP00000030274	Thioredoxin interacting protein.	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.761