Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
U3ICV3_ANAPPUncharacterized protein. (2270 aa)    
Predicted Functional Partners:
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.810
ADGRF5
Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.801
TEK
TEK receptor tyrosine kinase.
   
 0.683
ENSAPLP00000021042
Uncharacterized protein.
      
 0.547
SLC25A12
Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.546
TP73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
      
 0.544
APMAP
Adipocyte plasma membrane associated protein.
      
 0.537
TBC1D31
TBC1 domain family member 31.
      
 0.493
PTS
6-pyruvoyltetrahydropterin synthase.
    
 
 0.491
FLT1
Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.484
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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