STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (674 aa)    
Predicted Functional Partners:
CYP46A1
Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.
 
 
 
 0.929
CYP4V2
Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family.
 
 
 
 0.929
U3IPW5_ANAPP
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
 
 
 0.929
TBXAS1
Thromboxane A synthase 1; Belongs to the cytochrome P450 family.
 
  
 
 0.923
U3IDX4_ANAPP
Uncharacterized protein.
 
  
 
 0.912
NAT9
N-acetyltransferase 9 (putative).
 
      0.895
U3IIY7_ANAPP
Uncharacterized protein.
 
  
 
 0.875
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
   0.767
FAM20C
FAM20C golgi associated secretory pathway kinase.
 
  
  0.735
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
 
      0.734
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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