Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)    
Predicted Functional Partners:
SOD1
Superoxide dismutase 1.
   
 0.987
GPX8
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.979
GPX7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.953
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.948
GPX3
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
    
 0.947
GPX1
Glutathione peroxidase 1.
    
 0.946
GPX2
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
    
 0.936
U3IJE0_ANAPP
Uncharacterized protein.
   
 0.929
GOT1
Aspartate aminotransferase.
   
 
 0.927
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
  
 0.924
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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