Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
USP35Ubiquitin carboxyl-terminal hydrolase. (978 aa)    
Predicted Functional Partners:
WDR48
WD repeat domain 48.
    
 0.769
WDR20
WD repeat domain 20.
   
 0.708
USP44
Ubiquitinyl hydrolase 1.
      
 0.635
STING1
Transmembrane protein 173.
    
 
 0.608
MAVS
CARD_2 domain-containing protein.
    
   0.606
USP13
Ubiquitin carboxyl-terminal hydrolase.
      
 0.592
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.578
INPP4B
Inositol polyphosphate-4-phosphatase type II B.
      
 0.574
HHIP
Hedgehog interacting protein.
      
 0.557
ANAPC10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
      
 0.556
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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