Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANXA4Annexin. (296 aa)    
Predicted Functional Partners:
CD9
Tetraspanin.
   
 
 0.534
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.475
MANF
Mesencephalic astrocyte derived neurotrophic factor.
     
  0.452
TLN2
Talin 2.
     
 0.423
CD81
Tetraspanin.
   
  
 0.422
HABP4
Hyaluronan binding protein 4.
    
  0.414
ACTA1
Actin alpha 1, skeletal muscle.
    
 0.412
ACTC1
Actin alpha cardiac muscle 1.
    
 0.412
MEGF6
Multiple EGF like domains 6.
    
 0.410
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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