Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPR143G protein-coupled receptor 143. (408 aa)    
Predicted Functional Partners:
TYRP1
Tyrosinase related protein 1.
   
 
 0.842
MLANA
Melan-A.
   
 
 0.788
OTC
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
   
 0.753
FRMD7
FERM domain containing 7.
      
 0.746
DHODH
DHO_dh domain-containing protein.
  
 0.729
OCA2
OCA2 melanosomal transmembrane protein.
   
  
 0.714
MITF
Melanocyte inducing transcription factor.
     
 0.685
ASS1
Uncharacterized protein.
  
 
 0.673
ENSAPLP00000023817
Uncharacterized protein.
  
 
 0.673
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.672
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (14%) [HD]