Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (748 aa)    
Predicted Functional Partners:
POMC
Proopiomelanocortin.
    
 0.975
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.938
GHRL
Ghrelin and obestatin prepropeptide.
     
 0.922
PCSK9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
      
 0.871
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.871
MC4R
Melanocortin 4 receptor.
   
  
 0.761
GCG
Glucagon.
   
 
 0.729
FAP
Fibroblast activation protein alpha; Belongs to the peptidase S9B family.
   
 
 0.729
CPE
Carboxypeptidase E.
   
  
 0.670
ENSAPLP00000029215
Uncharacterized protein.
      
 0.666
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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