Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
NEK3NIMA related kinase 3; Belongs to the protein kinase superfamily. (500 aa)    
Predicted Functional Partners:
NEK8
Uncharacterized protein.
 
    
 0.746
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
    
 0.507
GTF2F2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
      
 0.503
NEK2
NIMA related kinase 2.
   
 
 0.494
CDC25A
Cell division cycle 25A.
   
 0.478
SPERT
Uncharacterized protein.
    
 0.462
DLGAP5
DLG associated protein 5.
   
  
 0.445
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
     
 0.445
WDFY2
WD repeat and FYVE domain containing 2.
    
 0.434
ME3
Malic enzyme.
    
  0.427
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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