Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
MAPK10Mitogen-activated protein kinase. (384 aa)    
Predicted Functional Partners:
MAPK9
Mitogen-activated protein kinase.
  
0.996
JUN
Jun proto-oncogene, AP-1 transcription factor subunit.
   
 0.996
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
  
0.994
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 0.989
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
0.983
DUSP10
Dual specificity phosphatase 10.
    
 0.978
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
   
 0.978
BCL2L1
BCL2 like 1.
    
 0.976
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
   
 0.975
CRK
CRK proto-oncogene, adaptor protein.
    
 0.971
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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