Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SBSPONSomatomedin B and thrombospondin type 1 domain containing. (267 aa)    
Predicted Functional Partners:
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 
 0.638
THSD7A
Thrombospondin type 1 domain containing 7A.
     
 0.627
PALB2
Partner and localizer of BRCA2.
  
 0.585
CABCOCO1
Uncharacterized protein.
    
 0.580
ENSAPLP00000031149
Uncharacterized protein.
    
 0.580
ZFAND6
Zinc finger AN1-type containing 6.
      
 0.560
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.556
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.548
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif 18.
     
 0.547
ABHD13
Abhydrolase domain containing 13.
      
 0.544
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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