Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SERGEFSecretion regulating guanine nucleotide exchange factor. (356 aa)    
Predicted Functional Partners:
DPH3
Diphthamide biosynthesis 3.
    
 
 0.956
ZNF536
Zinc finger protein 536.
    
 0.861
ATP6V1C1
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.849
EXOC2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
    
 
 0.798
TBC1D15
TBC1 domain family member 15.
   
  
 0.673
ATP6V1H
ATPase H+ transporting V1 subunit H.
      
 0.670
KCNJ11
Potassium voltage-gated channel subfamily J member 11.
     
 0.660
TMEM50B
Transmembrane protein 50B.
      
 0.649
USH1C
USH1 protein network component harmonin.
    
 
 0.643
SAAL1
Uncharacterized protein.
 
    
 0.607
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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