Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FGD6FYVE, RhoGEF and PH domain containing 6. (1451 aa)    
Predicted Functional Partners:
UHMK1
U2AF homology motif kinase 1.
      
 0.729
DBNL
Drebrin like.
    
 
 0.664
PPM1B
PPM-type phosphatase domain-containing protein.
      
 0.639
TMEM14A
Transmembrane protein 14A.
      
 0.598
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
      
 0.582
LYRM7
LYR motif containing 7; Belongs to the complex I LYR family.
      
 0.546
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1.
      
 0.545
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.488
NELL1
Neural EGFL like 1.
    
 
 0.487
NELL2
Neural EGFL like 2.
    
 
 0.487
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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