Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PRDM16PR/SET domain 16. (979 aa)    
Predicted Functional Partners:
ENSAPLP00000022312
Uncharacterized protein.
 
      0.900
TMEM26
Transmembrane protein 26.
      
 0.782
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
    
 0.730
ENSAPLP00000020360
Uncharacterized protein.
    
 0.699
PPARGC1A
PPARG coactivator 1 alpha.
    
 0.682
CIDEA
Cell death inducing DFFA like effector a.
     
 0.663
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
     
 0.650
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
     
 0.650
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
  0.650
ZNF516
Zinc finger protein 516.
    
 
 0.649
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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