Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEC61A2SEC61 translocon alpha 2 subunit. (476 aa)    
Predicted Functional Partners:
SEC61B
SEC61 translocon beta subunit.
   
 0.991
SEC61G
SEC61 translocon gamma subunit.
   
 0.990
SEC63
SEC63 homolog, protein translocation regulator.
   
 
 0.971
RPL23
Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.952
RPL11
Ribosomal protein L11.
  
 
 0.952
RPL26
Ribosomal protein L26.
  
 
 0.951
RPS11
Ribosomal protein S11.
  
 
 0.932
RPL8
Ribosomal protein L8.
  
 
 0.930
RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 0.922
U3ILL9_ANAPP
Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family.
  
 
 0.921
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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