Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (789 aa)    
Predicted Functional Partners:
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
   
 
 0.919
ACE2
Angiotensin-converting enzyme.
      
 0.866
NRP1
Neuropilin; Belongs to the neuropilin family.
      
 0.797
CTSL
Uncharacterized protein; Belongs to the peptidase C1 family.
  
 
 0.769
ADAM17
ADAM metallopeptidase domain 17.
     
 0.727
MMP11
Matrix metallopeptidase 11.
    
 0.721
NOTCH1
Uncharacterized protein.
   
 0.714
ENSAPLP00000028254
Uncharacterized protein.
   
 0.714
FBN1
Fibrillin 1.
   
 0.711
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 
 0.709
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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