TNPO3 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TNPO3

Transportin 3. (438 aa)

Predicted Functional Partners:

IRAK2

0.871

RAN

0.788

CPSF6

0.757

TNPO1

0.693

GNL3

0.690

ADGRD1

0.682

ENSAPLP00000020419

0.676

NUP155

0.669

U3I3U3_ANAPP

0.668

SRSF4

0.668

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRD1	TNPO1	ENSAPLP00000026172	ENSAPLP00000009385	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	Transportin 1.	0.792
ADGRD1	TNPO3	ENSAPLP00000026172	ENSAPLP00000005575	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	Transportin 3.	0.682
CPSF6	NUP155	ENSAPLP00000024692	ENSAPLP00000019047	RRM domain-containing protein.	Nucleoporin 155.	0.580
CPSF6	SRSF4	ENSAPLP00000024692	ENSAPLP00000006211	RRM domain-containing protein.	Serine and arginine rich splicing factor 4.	0.515
CPSF6	TNPO3	ENSAPLP00000024692	ENSAPLP00000005575	RRM domain-containing protein.	Transportin 3.	0.757
CPSF6	U3I3U3_ANAPP	ENSAPLP00000024692	ENSAPLP00000001914	RRM domain-containing protein.	Uncharacterized protein.	0.515
ENSAPLP00000020419	TNPO3	ENSAPLP00000020419	ENSAPLP00000005575	NR LBD domain-containing protein.	Transportin 3.	0.676
GNL3	IRAK2	ENSAPLP00000004761	ENSAPLP00000003176	G protein nucleolar 3.	Interleukin 1 receptor associated kinase 2.	0.731
GNL3	TNPO3	ENSAPLP00000004761	ENSAPLP00000005575	G protein nucleolar 3.	Transportin 3.	0.690
IRAK2	GNL3	ENSAPLP00000003176	ENSAPLP00000004761	Interleukin 1 receptor associated kinase 2.	G protein nucleolar 3.	0.731
IRAK2	TNPO3	ENSAPLP00000003176	ENSAPLP00000005575	Interleukin 1 receptor associated kinase 2.	Transportin 3.	0.871
NUP155	CPSF6	ENSAPLP00000019047	ENSAPLP00000024692	Nucleoporin 155.	RRM domain-containing protein.	0.580
NUP155	TNPO1	ENSAPLP00000019047	ENSAPLP00000009385	Nucleoporin 155.	Transportin 1.	0.461
NUP155	TNPO3	ENSAPLP00000019047	ENSAPLP00000005575	Nucleoporin 155.	Transportin 3.	0.669
RAN	TNPO1	ENSAPLP00000013416	ENSAPLP00000009385	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Transportin 1.	0.903
RAN	TNPO3	ENSAPLP00000013416	ENSAPLP00000005575	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Transportin 3.	0.788
SRSF4	CPSF6	ENSAPLP00000006211	ENSAPLP00000024692	Serine and arginine rich splicing factor 4.	RRM domain-containing protein.	0.515
SRSF4	TNPO3	ENSAPLP00000006211	ENSAPLP00000005575	Serine and arginine rich splicing factor 4.	Transportin 3.	0.668
TNPO1	ADGRD1	ENSAPLP00000009385	ENSAPLP00000026172	Transportin 1.	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.	0.792
TNPO1	NUP155	ENSAPLP00000009385	ENSAPLP00000019047	Transportin 1.	Nucleoporin 155.	0.461