Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMCR8SMCR8-C9orf72 complex subunit. (882 aa)    
Predicted Functional Partners:
C9orf72
C9orf72-SMCR8 complex subunit.
    
 0.998
WDR41
WD repeat domain 41.
    
 0.993
RAB39B
RAB39B, member RAS oncogene family.
    
 0.959
ULK2
Unc-51 like autophagy activating kinase 2.
    
 0.940
RAB8A
RAB8A, member RAS oncogene family.
    
 0.928
TBK1
TANK binding kinase 1.
   
 0.927
TANK
TRAF family member associated NFKB activator.
     
 0.911
ENSAPLP00000020863
Uncharacterized protein.
    
 0.903
FLCN
UDENN FLCN/SMCR8-type domain-containing protein.
      
 0.871
FNIP1
Folliculin interacting protein 1.
    
 
 0.761
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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