STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASRCalcium sensing receptor. (1059 aa)    
Predicted Functional Partners:
GPRC6A
ANF_receptor domain-containing protein.
     
0.930
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.917
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.
      
 0.748
GCM2
Glial cells missing transcription factor 2.
   
 
 0.614
TRPV6
Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.586
ENSAPLP00000016618
WD_REPEATS_REGION domain-containing protein.
    
  0.573
WDR90
Uncharacterized protein.
    
  0.573
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
    
0.519
GABBR1
G_PROTEIN_RECEP_F3_4 domain-containing protein.
    
 0.519
GRM2
Glutamate metabotropic receptor 2.
    
 
0.512
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.