STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHD7Chromodomain helicase DNA binding protein 7. (2936 aa)    
Predicted Functional Partners:
ARID4A
AT-rich interaction domain 4A.
   
 0.830
PSMD4
Proteasome 26S subunit, non-ATPase 4.
      
 0.710
OTUD7B
OTU deubiquitinase 7B.
    
 
 0.704
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
    
 
 0.640
SLC25A15
Solute carrier family 25 member 15; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.632
U3J5M8_ANAPP
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
     
 0.614
ANOS1
Anosmin 1.
      
 0.594
ENSAPLP00000028245
Uncharacterized protein.
    
 0.588
FANCM
FA complementation group M.
    
 0.585
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.580
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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