| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACAT2 | ACOX1 | ENSAPLP00000005650 | ENSAPLP00000016006 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.951 |
| ACAT2 | ACOX3 | ENSAPLP00000005650 | ENSAPLP00000010386 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.951 |
| ACAT2 | CS | ENSAPLP00000005650 | ENSAPLP00000032070 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.960 |
| ACAT2 | EHHADH | ENSAPLP00000005650 | ENSAPLP00000019039 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3HCDH_N domain-containing protein. | 0.958 |
| ACAT2 | HADH | ENSAPLP00000005650 | ENSAPLP00000007044 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase. | 0.978 |
| ACAT2 | HADHA | ENSAPLP00000005650 | ENSAPLP00000003377 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.962 |
| ACAT2 | HMGCLL1 | ENSAPLP00000005650 | ENSAPLP00000020894 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.951 |
| ACAT2 | HMGCS1 | ENSAPLP00000005650 | ENSAPLP00000016593 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.989 |
| ACAT2 | HMGCS2 | ENSAPLP00000005650 | ENSAPLP00000022122 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.980 |
| ACAT2 | OXCT1 | ENSAPLP00000005650 | ENSAPLP00000017236 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.961 |
| ACOX1 | ACAT2 | ENSAPLP00000016006 | ENSAPLP00000005650 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.951 |
| ACOX1 | ACOX3 | ENSAPLP00000016006 | ENSAPLP00000010386 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.964 |
| ACOX1 | CS | ENSAPLP00000016006 | ENSAPLP00000032070 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.497 |
| ACOX1 | EHHADH | ENSAPLP00000016006 | ENSAPLP00000019039 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 3HCDH_N domain-containing protein. | 0.987 |
| ACOX1 | HADH | ENSAPLP00000016006 | ENSAPLP00000007044 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Hydroxyacyl-CoA dehydrogenase. | 0.647 |
| ACOX1 | HADHA | ENSAPLP00000016006 | ENSAPLP00000003377 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.976 |
| ACOX1 | HMGCLL1 | ENSAPLP00000016006 | ENSAPLP00000020894 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.586 |
| ACOX1 | HMGCS2 | ENSAPLP00000016006 | ENSAPLP00000022122 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.543 |
| ACOX1 | OXCT1 | ENSAPLP00000016006 | ENSAPLP00000017236 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.451 |
| ACOX3 | ACAT2 | ENSAPLP00000010386 | ENSAPLP00000005650 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.951 |