Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOXL2Lysyl oxidase like 2. (789 aa)    
Predicted Functional Partners:
DHX15
DEAH-box helicase 15.
    
  0.765
ENSAPLP00000025208
Uncharacterized protein.
    
 0.611
GALNT14
Polypeptide N-acetylgalactosaminyltransferase.
     
 0.450
COL8A2
Collagen type VIII alpha 2 chain.
    
 0.445
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 0.440
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7.
    
 0.437
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif 8.
    
 0.435
IMPG2
Interphotoreceptor matrix proteoglycan 2.
      
 0.419
PPIP5K2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
      
 0.419
CPSF3
Uncharacterized protein.
     
 0.414
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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