Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HYOU1Hypoxia up-regulated 1. (989 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
  
0.997
SIL1
SIL1 nucleotide exchange factor.
   
 0.990
PDIA4
Protein disulfide-isomerase.
   
 0.958
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.927
SEC63
SEC63 homolog, protein translocation regulator.
  
 
 0.884
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
 0.832
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
  
 0.825
DNAJB11
J domain-containing protein.
  
 0.801
CRELD2
Cysteine rich with EGF like domains 2.
   
 
 0.795
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
  
 
 0.794
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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