Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)    
Predicted Functional Partners:
ENSAPLP00000022103
Brix domain-containing protein.
      
 0.612
P2RX7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
   
  0.596
P2RX2
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
    
 0.587
P2RX3
Purinergic receptor P2X 3.
     
 0.561
P2RY4
Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family.
      
 0.550
P2RY6
Pyrimidinergic receptor P2Y6.
      
 0.548
P2RY1
Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family.
     
 0.547
GOLIM4
Golgi integral membrane protein 4.
      
 0.546
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
   0.538
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
    
 0.500
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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